A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities. [electronic resource]
Producer: 20140404Description: 325-34 p. digitalISSN:- 1768-3254
- Angiogenesis Inhibitors -- chemical synthesis
- Biomarkers, Tumor -- antagonists & inhibitors
- Cell Line, Tumor
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- chemical synthesis
- Humans
- Kinetics
- Matrix Metalloproteinase 9 -- biosynthesis
- Molecular Structure
- Structure-Activity Relationship
- Thymidine Phosphorylase -- antagonists & inhibitors
- Triazines -- chemical synthesis
- Triazoles -- chemical synthesis
- Vascular Endothelial Growth Factors -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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