Thrombin mutants with altered enzymatic activity have an impaired mitogenic effect on mouse fibroblasts and are inefficient modulators of stellation of rat cortical astrocytes. [electronic resource]
Producer: 19991001Description: 173-86 p. digitalISSN:- 0006-3002
- 3T3 Cells
- Animals
- Astrocytes -- drug effects
- Blood Coagulation -- drug effects
- Bucladesine -- pharmacology
- Cell Differentiation
- Cells, Cultured
- Chromogenic Compounds -- metabolism
- DNA, Complementary -- genetics
- Dipeptides -- metabolism
- Endopeptidases -- pharmacology
- Enzyme Activation -- drug effects
- Enzyme Precursors -- biosynthesis
- Mice
- Microscopy, Phase-Contrast
- Mitogens -- genetics
- Point Mutation
- Prothrombin -- biosynthesis
- Rats
- Rats, Wistar
- Receptors, Thrombin -- drug effects
- Reverse Transcriptase Polymerase Chain Reaction
- Thrombin -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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