Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models. [electronic resource]
Producer: 20181218Description: 581-593 p. digitalISSN:- 1768-3254
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Lung Neoplasms -- drug therapy
- Mice
- Mice, Inbred C57BL
- Models, Molecular
- Molecular Structure
- Neoplasms, Experimental -- drug therapy
- Phosphoric Diester Hydrolases -- metabolism
- Quantum Theory
- Structure-Activity Relationship
- Topoisomerase I Inhibitors -- chemical synthesis
- Topotecan -- chemical synthesis
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Publication Type: Journal Article
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