Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway. [electronic resource]
Producer: 20060525Description: 26 p. digitalISSN:- 1471-2407
- Apoptosis
- Blotting, Western
- Carcinoma, Non-Small-Cell Lung -- metabolism
- Cell Line, Tumor
- Culture Media -- metabolism
- Deoxyglucose -- chemistry
- Down-Regulation
- Flow Cytometry
- Genetic Vectors
- Glucose Transporter Type 1 -- metabolism
- Glycolysis
- HEPES -- chemistry
- Hexokinase -- metabolism
- Humans
- Hydrogen-Ion Concentration
- Hypoxia
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- In Situ Nick-End Labeling
- Lactates -- chemistry
- Lung Neoplasms -- metabolism
- Models, Statistical
- Oxygen -- metabolism
- Phosphoglycerate Kinase -- metabolism
- Plasmids -- metabolism
- RNA -- chemistry
- RNA, Messenger -- metabolism
- RNA, Small Interfering -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Time Factors
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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