Computational screening of chalcones acting against topoisomerase IIα and their cytotoxicity towards cancer cell lines. [electronic resource]
Producer: 20181108Description: 134-143 p. digitalISSN:- 1475-6374
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chalcones -- chemical synthesis
- DNA Topoisomerases, Type II -- metabolism
- Drug Design
- Drug Screening Assays, Antitumor
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation -- drug effects
- HeLa Cells
- Humans
- Inhibitory Concentration 50
- Models, Molecular
- Molecular Docking Simulation
- Neoplasms -- drug therapy
- Structure-Activity Relationship
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Publication Type: Journal Article
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