SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a [electronic resource]
Producer: 20190812ISSN:- 1754-8411
- Amyotrophic Lateral Sclerosis -- metabolism
- Animals
- Autophagy
- Brain -- metabolism
- Carrier Proteins -- metabolism
- Cells, Cultured
- Disease Models, Animal
- Drosophila Proteins -- metabolism
- Drosophila melanogaster -- metabolism
- Larva -- metabolism
- Membrane Proteins -- metabolism
- Models, Biological
- Oxidative Stress
- Proteasome Endopeptidase Complex -- metabolism
- Protein Aggregates
- Proteolysis
- RNA, Double-Stranded -- metabolism
- Reactive Oxygen Species -- metabolism
- Receptor Protein-Tyrosine Kinases -- metabolism
- Reverse Genetics
- Signal Transduction
- Superoxide Dismutase -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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