AZD3759 induces apoptosis in hepatoma cells by activating a p53-SMAD4 positive feedback loop. [electronic resource]
Producer: 20191028Description: 535-540 p. digitalISSN:- 1090-2104
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Hepatocellular -- drug therapy
- Gene Expression Regulation, Neoplastic -- drug effects
- Hep G2 Cells
- Humans
- Liver Neoplasms -- drug therapy
- Piperazines -- pharmacology
- Quinazolines -- pharmacology
- Signal Transduction -- drug effects
- Smad4 Protein -- genetics
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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