Hepatic cholesterol accumulation ascribed to the activation of ileum Fxr-Fgf15 pathway inhibiting hepatic Cyp7a1 in high-fat diet-induced obesity rats. [electronic resource]
Producer: 20190927Description: 116638 p. digitalISSN:- 1879-0631
- Animals
- Bile Acids and Salts -- metabolism
- Caco-2 Cells
- Cholesterol -- metabolism
- Cholesterol 7-alpha-Hydroxylase -- antagonists & inhibitors
- Diet, High-Fat
- Fibroblast Growth Factors -- metabolism
- Humans
- Ileum -- metabolism
- Liver -- metabolism
- Male
- Membrane Transport Proteins -- metabolism
- Obesity -- enzymology
- Rats
- Rats, Wistar
- Receptors, Cytoplasmic and Nuclear -- metabolism
- Signal Transduction
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Publication Type: Journal Article
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