Gefitinib enhances cytotoxicities of antimicrotubule agents in non-small-cell lung cancer cells exhibiting no sensitizing epidermal growth factor receptor mutation. [electronic resource]
Producer: 20121214Description: 1218-27 p. digitalISSN:- 1556-1380
- Antineoplastic Agents -- pharmacology
- Antineoplastic Combined Chemotherapy Protocols
- Apoptosis -- drug effects
- Blotting, Western
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Drug Resistance, Multiple
- Drug Resistance, Neoplasm
- Drug Synergism
- ErbB Receptors -- genetics
- Gefitinib
- Genes, MDR -- genetics
- Humans
- Lung Neoplasms -- drug therapy
- Microtubules -- drug effects
- Mutation -- genetics
- Paclitaxel -- pharmacology
- Quinazolines -- pharmacology
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Tubulin Modulators -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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