A monoclonal antibody to the human HER3 receptor inhibits Neuregulin 1-beta binding and co-operates with Herceptin in inhibiting the growth of breast cancer derived cell lines. [electronic resource]
Producer: 20121119Description: 53-9 p. digitalISSN:- 1573-7217
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized -- pharmacology
- Antineoplastic Agents -- pharmacology
- Binding, Competitive
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor -- drug effects
- Cell Proliferation -- drug effects
- Drug Screening Assays, Antitumor
- Drug Synergism
- Female
- Humans
- Neuregulin-1 -- metabolism
- Protein Binding
- Receptor, ErbB-3 -- antagonists & inhibitors
- Trastuzumab
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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