RAS mutations are associated with the development of cutaneous squamous cell tumors in patients treated with RAF inhibitors. [electronic resource]
Producer: 20120531Description: 316-21 p. digitalISSN:- 1527-7755
- Adult
- Aged
- Aged, 80 and over
- Benzenesulfonates -- adverse effects
- Carcinoma, Squamous Cell -- chemically induced
- Female
- Gene Expression Regulation, Neoplastic
- Genotype
- Humans
- Indoles -- adverse effects
- Male
- Mass Spectrometry
- Middle Aged
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Mutation
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds
- Protein Kinase Inhibitors -- adverse effects
- Proto-Oncogene Proteins B-raf -- antagonists & inhibitors
- Pyridines -- adverse effects
- Skin Neoplasms -- chemically induced
- Sorafenib
- Sulfonamides -- adverse effects
- Vemurafenib
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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