In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach. [electronic resource]
Producer: 20141009Description: 421-36 p. digitalISSN:- 1742-2051
- Amino Acid Substitution
- Computer Simulation
- Humans
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Mutation, Missense
- Open Reading Frames
- Polymorphism, Single Nucleotide
- Protein Binding
- Protein Conformation
- Protein Interaction Domains and Motifs -- genetics
- Protein Kinase Inhibitors -- chemistry
- Protein Processing, Post-Translational
- Proto-Oncogene Proteins c-ret -- antagonists & inhibitors
- Reproducibility of Results
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Publication Type: Journal Article
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