Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats. [electronic resource]
Producer: 20120123Description: 1590-601 p. digitalISSN:- 1473-5598
- Angiotensin II Type 1 Receptor Blockers -- pharmacology
- Animals
- Blood Pressure -- drug effects
- Cytochrome P-450 CYP1A1 -- genetics
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Epoxide Hydrolases -- antagonists & inhibitors
- Glomerular Filtration Rate -- drug effects
- Hypertension, Malignant -- chemically induced
- Indoles -- adverse effects
- Kidney -- blood supply
- Kidney Diseases -- physiopathology
- Losartan -- pharmacology
- Natriuresis -- drug effects
- Rats
- Rats, Transgenic
- Regional Blood Flow -- drug effects
- Renin -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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