Genetically modified HLA class I molecules able to inhibit human NK cells without provoking alloreactive CD8+ CTLs. [electronic resource]
Producer: 20020508Description: 3266-74 p. digitalISSN:- 0022-1767
- Aspartic Acid -- genetics
- Cell Death -- genetics
- Cell Line
- Cell Line, Transformed -- immunology
- Clone Cells
- Cytotoxicity Tests, Immunologic
- Cytotoxicity, Immunologic -- genetics
- Dose-Response Relationship, Immunologic
- Down-Regulation -- genetics
- Genetic Vectors -- immunology
- HLA-C Antigens -- biosynthesis
- Humans
- Immunophenotyping
- Killer Cells, Natural -- immunology
- Lymphocyte Activation -- genetics
- Lymphocyte Subsets -- immunology
- Lysine -- genetics
- Mutagenesis, Site-Directed
- Receptors, Immunologic -- metabolism
- Receptors, KIR
- T-Lymphocytes, Cytotoxic -- immunology
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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