NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells. [electronic resource]
Producer: 20060921Description: 1547-52 p. digitalISSN:- 0020-7136
- Activating Transcription Factor 1
- Adenocarcinoma -- genetics
- Cell Line
- Cyclic AMP Response Element-Binding Protein -- metabolism
- DNA -- biosynthesis
- DNA-Binding Proteins -- metabolism
- Enzyme Activation -- drug effects
- Epithelial Cells -- cytology
- ErbB Receptors -- genetics
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Humans
- Lung -- cytology
- Lung Neoplasms -- genetics
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Mutation -- genetics
- Nitrosamines -- pharmacology
- Nuclear Proteins -- metabolism
- Phosphorylation -- drug effects
- Receptors, Adrenergic, beta-1 -- metabolism
- Regulatory Factor X Transcription Factors
- Signal Transduction -- drug effects
- Transcription Factors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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