Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young. [electronic resource]
Producer: 20050621Description: 14105-13 p. digitalISSN:- 0021-9258
- Adaptor Proteins, Signal Transducing
- Animals
- Binding Sites
- Carrier Proteins -- metabolism
- Child
- DNA Mutational Analysis
- Diabetes Mellitus, Type 2 -- genetics
- Enzyme Activation
- Enzyme Stability
- Female
- Glucokinase -- genetics
- Glucose -- metabolism
- Humans
- Hyperglycemia -- genetics
- Infant, Newborn
- Male
- Models, Molecular
- Pedigree
- Point Mutation
- Pregnancy
- Protein Structure, Tertiary
- Recombinant Fusion Proteins -- genetics
- Recombinant Proteins -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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