The e13a2 BCR-ABL transcript negatively affects sustained deep molecular response and the achievement of treatment-free remission in patients with chronic myeloid leukemia who receive tyrosine kinase inhibitors. [electronic resource]
Producer: 20200211Description: 1674-1682 p. digitalISSN:- 1097-0142
- Academic Medical Centers
- Adult
- Aged
- Aged, 80 and over
- Cohort Studies
- Disease-Free Survival
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Female
- Fusion Proteins, bcr-abl -- genetics
- Gene Expression Regulation, Neoplastic
- Humans
- Imatinib Mesylate -- administration & dosage
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- drug therapy
- Male
- Middle Aged
- Molecular Targeted Therapy -- methods
- Multivariate Analysis
- Prognosis
- Proportional Hazards Models
- Protein Kinase Inhibitors -- administration & dosage
- Real-Time Polymerase Chain Reaction -- methods
- Retrospective Studies
- Survival Analysis
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Publication Type: Comparative Study; Journal Article
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