BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER. [electronic resource]
Producer: 20121025Description: 3282-96 p. digitalISSN:- 1460-2075
- Amino Acid Sequence
- Calcium -- metabolism
- Calcium Signaling -- drug effects
- Endoplasmic Reticulum -- drug effects
- Endoplasmic Reticulum Chaperone BiP
- Gene Silencing -- physiology
- HeLa Cells
- Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Ion Channel Gating -- drug effects
- Ion Transport -- drug effects
- Membrane Proteins -- chemistry
- Models, Molecular
- Molecular Sequence Data
- Protein Binding -- drug effects
- Protein Folding -- drug effects
- RNA, Small Interfering -- pharmacology
- SEC Translocation Channels
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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