An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene. [electronic resource]
Producer: 20170613Description: 7292-303 p. digitalISSN:- 1362-4962
- Benzodioxoles -- pharmacology
- DNA Gyrase -- genetics
- DNA Topoisomerases, Type I -- biosynthesis
- DNA, Bacterial -- drug effects
- DNA, Superhelical -- drug effects
- Gene Expression Regulation, Bacterial -- drug effects
- Genes, Bacterial -- genetics
- Homeostasis -- drug effects
- Microbial Viability -- drug effects
- Multigene Family
- Phenanthrenes -- pharmacology
- Streptococcus pneumoniae -- drug effects
- Transcription, Genetic -- drug effects
- Transcriptome -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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