Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice. [electronic resource]
Producer: 20131202Description: e54712 p. digitalISSN:- 1932-6203
- Administration, Oral
- Animals
- Antibodies, Monoclonal -- immunology
- Antigens, CD20 -- immunology
- B-Lymphocytes -- cytology
- CD4-Positive T-Lymphocytes -- drug effects
- Diabetes Mellitus, Type 1 -- drug therapy
- Drug Therapy, Combination -- methods
- Female
- Hyperglycemia -- drug therapy
- Insulin -- administration & dosage
- Interleukin-4 -- immunology
- Lymph Nodes -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Inbred NOD
- Pancreas -- drug effects
- Proinsulin -- administration & dosage
- Spleen -- drug effects
- Vaccines, DNA -- administration & dosage
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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