Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein. [electronic resource]
Producer: 20110208Description: 287-96 p. digitalISSN:- 1520-7560
- Animals
- Diabetes Mellitus, Type 2 -- drug therapy
- Genes, Reporter
- Glucagon-Like Peptide-1 Receptor
- Glucagon-Like Peptides -- analogs & derivatives
- Humans
- Immunoglobulin Fc Fragments -- genetics
- Incretins -- genetics
- Insulin -- metabolism
- Insulin Secretion
- Islets of Langerhans -- metabolism
- Macaca fascicularis
- Membrane Proteins -- genetics
- Mice
- Mitochondrial Proteins -- genetics
- Protein Engineering
- Rats
- Rats, Sprague-Dawley
- Receptors, Glucagon -- agonists
- Recombinant Fusion Proteins -- genetics
- beta-Lactamases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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