Transfected MDCK cell line with enhanced expression of CYP3A4 and P-glycoprotein as a model to study their role in drug transport and metabolism. [electronic resource]
Producer: 20140929Description: 1877-86 p. digitalISSN:- 1543-8392
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Animals
- Biological Transport -- drug effects
- Caco-2 Cells
- Cell Line
- Cell Line, Tumor
- Cytochrome P-450 CYP3A -- genetics
- Dogs
- Drug Interactions -- genetics
- Flavanones -- pharmacology
- Hep G2 Cells
- Humans
- Hydrocortisone -- pharmacology
- Ketoconazole -- pharmacology
- Madin Darby Canine Kidney Cells
- Morphine -- pharmacology
- Permeability
- Transfection -- methods
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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