Which cytochrome P450 metabolizes phenazepam? Step by step in silico, in vitro, and in vivo studies. [electronic resource]
Producer: 20181211Description: 65-73 p. digitalISSN:- 2363-8915
- Benzodiazepines -- metabolism
- Biomarkers -- blood
- Bioreactors
- Cell Culture Techniques -- instrumentation
- Cells, Cultured
- Computer Simulation
- Cytochrome P-450 CYP3A -- metabolism
- Hepatocytes -- enzymology
- Humans
- Hydrocortisone -- analogs & derivatives
- Hypnotics and Sedatives -- blood
- Isoenzymes
- Liver -- enzymology
- Models, Biological
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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