Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol. [electronic resource]
Producer: 20061130Description: 1237-42 p. digitalISSN:- 0091-6765
- Adult
- Aged
- Alcohol Dehydrogenase -- genetics
- Aldehyde Dehydrogenase -- genetics
- Animals
- Chloral Hydrate -- metabolism
- Cryopreservation
- Ethylene Chlorohydrin -- analogs & derivatives
- Female
- Genotype
- Hepatocytes -- drug effects
- Humans
- In Vitro Techniques
- Kinetics
- Male
- Middle Aged
- Rats
- Rats, Sprague-Dawley
- Reproducibility of Results
- Risk Assessment
- Solvents -- toxicity
- Trichloroacetic Acid -- metabolism
- Trichloroethylene -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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