DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death. [electronic resource]
Producer: 20191022Description: 17862 p. digitalISSN:- 2045-2322
- Animals
- Antineoplastic Agents -- administration & dosage
- Azocines -- administration & dosage
- Benzhydryl Compounds -- administration & dosage
- Carboplatin -- administration & dosage
- Caspase 9 -- analysis
- Cell Line, Tumor
- Cell Survival -- drug effects
- Disease Models, Animal
- Drug Resistance, Neoplasm -- drug effects
- Female
- Heterografts
- Humans
- Inhibitor of Apoptosis Proteins -- analysis
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Ovarian Neoplasms -- drug therapy
- Treatment Outcome
- X-Linked Inhibitor of Apoptosis Protein -- analysis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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