X-ray structure based evaluation of analogs of citalopram: Compounds with increased affinity and selectivity compared with R-citalopram for the allosteric site (S2) on hSERT. [electronic resource]
Producer: 20170704Description: 470-478 p. digitalISSN:- 1464-3405
- Allosteric Site
- Binding Sites
- Citalopram -- analogs & derivatives
- Crystallography, X-Ray
- Drug Design
- Humans
- Inhibitory Concentration 50
- Molecular Dynamics Simulation
- Protein Structure, Tertiary
- Serotonin Plasma Membrane Transport Proteins -- chemistry
- Selective Serotonin Reuptake Inhibitors -- chemical synthesis
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article
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