Triptycenes: a novel synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro. [electronic resource]
Producer: 20000104Description: 749-66 p. digitalISSN:- 0959-4973
- Animals
- Antineoplastic Agents -- chemical synthesis
- Biological Transport
- Bridged-Ring Compounds -- chemical synthesis
- Cell Survival -- drug effects
- DNA, Neoplasm -- biosynthesis
- Daunorubicin -- pharmacology
- Dose-Response Relationship, Drug
- Leukemia L1210 -- pathology
- Mice
- Mitosis -- drug effects
- Nucleosides -- metabolism
- Quinones -- chemical synthesis
- Time Factors
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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