Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells. [electronic resource]
Producer: 20040406Description: 1165-73 p. digitalISSN:- 0022-3565
- Animals
- Cells, Cultured
- Cholesterol -- metabolism
- Cholesterol Esters -- metabolism
- Esterification -- drug effects
- Estrogen Antagonists -- pharmacology
- Foam Cells -- drug effects
- Humans
- Lipoproteins, LDL -- pharmacology
- Macrophages, Peritoneal -- drug effects
- Male
- Rats
- Rats, Sprague-Dawley
- Receptors, Estrogen -- antagonists & inhibitors
- Sterol O-Acyltransferase -- antagonists & inhibitors
- Structure-Activity Relationship
- Tamoxifen -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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