Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells. [electronic resource]
Producer: 20171120Description: e2716 p. digitalISSN:- 2041-4889
- Autophagy-Related Protein 5 -- genetics
- Cell Line, Tumor
- Dynamins
- Electron Transport Complex I -- antagonists & inhibitors
- GTP Phosphohydrolases -- genetics
- HSP90 Heat-Shock Proteins -- genetics
- Humans
- Melanoma -- drug therapy
- Microtubule-Associated Proteins -- genetics
- Mitochondrial Membrane Transport Proteins -- genetics
- Mitochondrial Permeability Transition Pore
- Mitochondrial Proteins -- genetics
- Mitophagy
- Oxadiazoles -- pharmacology
- Protein Kinases -- genetics
- Pyrazoles -- pharmacology
- Reactive Oxygen Species -- metabolism
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Publication Type: Journal Article
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