Synthesis of D-Ring Annulated Pyridosteroids from β-Formyl Enamides and Their Biological Evaluations. [electronic resource]
Producer: 20190924Description: 11-27 p. digitalISSN:- 2156-8944
- Alkynes -- chemistry
- Androstenes -- pharmacology
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Azasteroids -- chemistry
- Caspase Inhibitors -- chemical synthesis
- Caspases -- metabolism
- Cell Line, Tumor
- Cell Survival -- drug effects
- Drug Screening Assays, Antitumor
- Humans
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- Molecular Structure
- Pyridines -- chemical synthesis
- Steroids -- chemical synthesis
- Structure-Activity Relationship
- Thermodynamics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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