Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variants. [electronic resource]
Producer: 20190731Description: 10272-10285 p. digitalISSN:- 1362-4962
- Animals
- Base Sequence
- Binding Sites -- genetics
- CRISPR-Associated Proteins -- metabolism
- CRISPR-Cas Systems -- genetics
- Clustered Regularly Interspaced Short Palindromic Repeats
- Endonucleases -- metabolism
- Francisella -- enzymology
- HEK293 Cells
- Humans
- Mammals
- Mice
- Moraxella -- enzymology
- Protein Binding
- Substrate Specificity
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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