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Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148. [electronic resource] by
- Mackman, Richard L
- Lin, Kuei-Ying
- Boojamra, Constantine G
- Hui, Hon
- Douglas, Janet
- Grant, Deborah
- Petrakovsky, Oleg
- Prasad, Vidya
- Ray, Adrian S
- Cihlar, Tomas
Producer: 20080324
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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5.
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Intracellular metabolism of the nucleotide prodrug GS-9131, a potent anti-human immunodeficiency virus agent. [electronic resource] by
- Ray, Adrian S
- Vela, Jennifer E
- Boojamra, Constantine G
- Zhang, Lijun
- Hui, Hon
- Callebaut, Christian
- Stray, Kirsten
- Lin, Kuei-Ying
- Gao, Ying
- Mackman, Richard L
- Cihlar, Tomas
Producer: 20080429
In:
Antimicrobial agents and chemotherapy vol. 52
Availability: No items available.
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6.
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Evaluation of 2'-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase. [electronic resource] by
- Parrish, Jay P
- Lee, Sharon K
- Boojamra, Constantine G
- Hui, Hon
- Babusis, Darius
- Brown, Brandon
- Shih, I-hung
- Feng, Joy Y
- Ray, Adrian S
- Mackman, Richard L
Producer: 20131209
In:
Bioorganic & medicinal chemistry letters vol. 23
Availability: No items available.
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7.
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Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs. [electronic resource] by
- Mackman, Richard L
- Zhang, Lijun
- Prasad, Vidya
- Boojamra, Constantine G
- Douglas, Janet
- Grant, Deborah
- Hui, Hon
- Kim, Choung U
- Laflamme, Genevieve
- Parrish, Jay
- Stoycheva, Antitsa D
- Swaminathan, Swami
- Wang, Keyu
- Cihlar, Tomas
Producer: 20070921
In:
Bioorganic & medicinal chemistry vol. 15
Availability: No items available.
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Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. [electronic resource] by
- Lansdon, Eric B
- Samuel, Dharmaraj
- Lagpacan, Leanna
- Brendza, Katherine M
- White, Kirsten L
- Hung, Magdeleine
- Liu, Xiaohong
- Boojamra, Constantine G
- Mackman, Richard L
- Cihlar, Tomas
- Ray, Adrian S
- McGrath, Mary E
- Swaminathan, S
Producer: 20100414
In:
Journal of molecular biology vol. 397
Availability: No items available.
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Synthesis and anti-HIV activity of cyclic pyrimidine phosphonomethoxy nucleosides and their prodrugs: a comparison of phosphonates and corresponding nucleosides. [electronic resource] by
- Mackman, Richard L
- Zhang, Lijun
- Prasad, Vidya
- Boojamra, Constantine G
- Chen, James
- Douglas, Janet
- Grant, Deborah
- Laflamme, Genevieve
- Hui, Hon
- Kim, Choung U
- Parrish, Jay
- Stoycheva, Antitsa D
- Swaminathan, Swami
- Wang, KeYu
- Cihlar, Tomas
Producer: 20080211
In:
Nucleosides, nucleotides & nucleic acids vol. 26
Availability: No items available.
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10.
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Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates. [electronic resource] by
- Mackman, Richard L
- Boojamra, Constantine G
- Prasad, Vidya
- Zhang, Lijun
- Lin, Kuei-Ying
- Petrakovsky, Oleg
- Babusis, Darius
- Chen, James
- Douglas, Janet
- Grant, Deborah
- Hui, Hon C
- Kim, Choung U
- Markevitch, David Y
- Vela, Jennifer
- Ray, Adrian
- Cihlar, Tomas
Producer: 20080303
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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11.
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Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131. [electronic resource] by
- Cihlar, Tomas
- Ray, Adrian S
- Boojamra, Constantine G
- Zhang, Lijun
- Hui, Hon
- Laflamme, Genevieve
- Vela, Jennifer E
- Grant, Deborah
- Chen, James
- Myrick, Florence
- White, Kirsten L
- Gao, Ying
- Lin, Kuei-Ying
- Douglas, Janet L
- Parkin, Neil T
- Carey, Anne
- Pakdaman, Rowchanak
- Mackman, Richard L
Producer: 20080429
In:
Antimicrobial agents and chemotherapy vol. 52
Availability: No items available.
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12.
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Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors. [electronic resource] by
- Boojamra, Constantine G
- Parrish, Jay P
- Sperandio, David
- Gao, Ying
- Petrakovsky, Oleg V
- Lee, Sharon K
- Markevitch, David Y
- Vela, Jennifer E
- Laflamme, Genevieve
- Chen, James M
- Ray, Adrian S
- Barron, Abraham C
- Sparacino, Mark L
- Desai, Manoj C
- Kim, Choung U
- Cihlar, Tomas
- Mackman, Richard L
Producer: 20090916
In:
Bioorganic & medicinal chemistry vol. 17
Availability: No items available.
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13.
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Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148. [electronic resource] by
- Mackman, Richard L
- Ray, Adrian S
- Hui, Hon C
- Zhang, Lijun
- Birkus, Gabriel
- Boojamra, Constantine G
- Desai, Manoj C
- Douglas, Janet L
- Gao, Ying
- Grant, Deborah
- Laflamme, Genevieve
- Lin, Kuei-Ying
- Markevitch, David Y
- Mishra, Ruchika
- McDermott, Martin
- Pakdaman, Rowchanak
- Petrakovsky, Oleg V
- Vela, Jennifer E
- Cihlar, Tomas
Producer: 20100827
In:
Bioorganic & medicinal chemistry vol. 18
Availability: No items available.
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14.
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Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study. [electronic resource] by
- Mackman, Richard L
- Sangi, Michael
- Sperandio, David
- Parrish, Jay P
- Eisenberg, Eugene
- Perron, Michel
- Hui, Hon
- Zhang, Lijun
- Siegel, Dustin
- Yang, Hai
- Saunders, Oliver
- Boojamra, Constantine
- Lee, Gary
- Samuel, Dharmaraj
- Babaoglu, Kerim
- Carey, Anne
- Gilbert, Brian E
- Piedra, Pedro A
- Strickley, Robert
- Iwata, Quynh
- Hayes, Jaclyn
- Stray, Kirsten
- Kinkade, April
- Theodore, Dorothy
- Jordan, Robert
- Desai, Manoj
- Cihlar, Tomas
Producer: 20150507
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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