High Efficacy of Combination Therapy Using PI3K/AKT Inhibitors with Androgen Deprivation in Prostate Cancer Preclinical Models. [electronic resource]
Producer: 20160407Description: 1177-1185 p. digitalISSN:- 1873-7560
- Aniline Compounds -- pharmacology
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Castration -- methods
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chromones -- pharmacology
- Humans
- Male
- PTEN Phosphohydrolase -- deficiency
- Phosphoinositide-3 Kinase Inhibitors
- Prostatic Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Pyrimidines -- pharmacology
- Pyrroles -- pharmacology
- Receptors, Androgen -- metabolism
- Signal Transduction -- drug effects
- Treatment Outcome
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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