Anagrelide metabolite induces thrombocytopenia in mice by inhibiting megakaryocyte maturation without inducing platelet aggregation. [electronic resource]
Producer: 20020124Description: 1417-24 p. digitalISSN:- 0301-472X
- Acetylcholinesterase -- analysis
- Animals
- Antigens, CD34 -- analysis
- Biomarkers -- analysis
- Cell Movement -- drug effects
- Cells, Cultured
- Chemokine CXCL12
- Chemokines, CXC -- pharmacology
- Fetal Blood -- immunology
- Humans
- Megakaryocytes -- pathology
- Mice
- Mice, Inbred BALB C
- Platelet Aggregation
- Platelet Aggregation Inhibitors -- pharmacology
- Platelet Count
- Ploidies
- Quinazolines -- pharmacology
- Thrombocytopenia -- physiopathology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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