Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver. [electronic resource]
Producer: 20160824Description: 2782-94 p. digitalISSN:- 1362-4962
- Animals
- Cell Adhesion Molecules, Neuronal -- genetics
- Clathrin-Coated Vesicles -- metabolism
- Endocytosis
- Endothelial Cells -- cytology
- Gene Expression
- HEK293 Cells
- Humans
- Kinetics
- Liver -- cytology
- Mice
- Oligonucleotides, Antisense -- chemical synthesis
- Phosphorothioate Oligonucleotides -- chemical synthesis
- Primary Cell Culture
- Protein Isoforms -- genetics
- RNA, Long Noncoding -- genetics
- Rats
- Rats, Sprague-Dawley
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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