Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes. [electronic resource]
Producer: 20110411Description: 2708-17 p. digitalISSN:- 1538-7836
- Anticoagulants -- chemistry
- Cell Line, Tumor
- Cytochrome P-450 Enzyme System -- genetics
- Fluorescence Resonance Energy Transfer
- Gene Expression Regulation, Enzymologic -- drug effects
- Genes, Reporter
- Humans
- Pregnane X Receptor
- Receptors, Steroid -- drug effects
- Reverse Transcriptase Polymerase Chain Reaction
- Stereoisomerism
- Transcriptional Activation
- Two-Hybrid System Techniques
- Up-Regulation -- drug effects
- Warfarin -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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