Simulations reveal that the HIV-1 gp120-CD4 complex dissociates via complex pathways and is a potential target of the polyamidoamine (PAMAM) dendrimer. [electronic resource]
Producer: 20140203Description: 024905 p. digitalISSN:- 1089-7690
- Anti-HIV Agents -- pharmacology
- Antigen-Antibody Complex -- immunology
- CD4 Antigens -- immunology
- Dendrimers -- pharmacology
- HIV Envelope Protein gp120 -- immunology
- HIV Infections -- drug therapy
- HIV-1 -- physiology
- Host-Pathogen Interactions
- Humans
- Molecular Dynamics Simulation
- Molecular Targeted Therapy
- Polyamines -- pharmacology
- Virus Internalization -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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