Insulin augmentation of 17alpha-hydroxylase activity is mediated by phosphatidyl inositol 3-kinase but not extracellular signal-regulated kinase-1/2 in human ovarian theca cells. [electronic resource]
Producer: 20040123Description: 175-83 p. digitalISSN:- 0013-7227
- Androgens -- biosynthesis
- Cells, Cultured
- Colforsin -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Female
- Flavonoids -- pharmacology
- Gene Expression Regulation, Enzymologic -- drug effects
- Humans
- Hypoglycemic Agents -- pharmacology
- Insulin -- pharmacology
- MAP Kinase Signaling System -- drug effects
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Polycystic Ovary Syndrome -- metabolism
- RNA, Messenger -- analysis
- Steroid 17-alpha-Hydroxylase -- genetics
- Theca Cells -- cytology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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