Paclitaxel-induced peripheral neuropathy is caused by epidermal ROS and mitochondrial damage through conserved MMP-13 activation. [electronic resource]
Producer: 20201126Description: 3970 p. digitalISSN:- 2045-2322
- Animals
- Axons -- drug effects
- Enzyme Activation -- drug effects
- Epidermis -- drug effects
- Matrix Metalloproteinase 13 -- metabolism
- Mitochondria -- drug effects
- Paclitaxel -- adverse effects
- Peripheral Nervous System Diseases -- chemically induced
- Reactive Oxygen Species -- metabolism
- Up-Regulation -- drug effects
- Zebrafish
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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