Generation and activity of a humanized monoclonal antibody that selectively neutralizes the epidermal growth factor receptor ligands transforming growth factor-α and epiregulin. [electronic resource]
Producer: 20140718Description: 330-43 p. digitalISSN:- 1521-0103
- Amino Acid Sequence
- Animals
- Animals, Newborn
- Antibodies, Monoclonal, Humanized -- metabolism
- Antibodies, Neutralizing -- metabolism
- Cell Line
- Cell Proliferation -- drug effects
- Epidermal Growth Factor -- metabolism
- Epiregulin
- ErbB Receptors -- metabolism
- Humans
- Immunoglobulin G -- immunology
- Macaca fascicularis
- Male
- Mice, Inbred C57BL
- Mice, Knockout
- Molecular Sequence Data
- Myofibroblasts -- cytology
- Protein Binding
- Transforming Growth Factor alpha -- genetics
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Publication Type: Journal Article
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