Nitric oxide/cGMP signaling inhibits TSH-stimulated iodide uptake and expression of thyroid peroxidase and thyroglobulin mRNA in FRTL-5 thyroid cells. [electronic resource]
Producer: 20080828Description: 717-27 p. digitalISSN:- 1050-7256
- Animals
- Carbazoles -- pharmacology
- Cell Line
- Cyclic AMP -- metabolism
- Cyclic GMP -- analogs & derivatives
- Cyclic GMP-Dependent Protein Kinases -- antagonists & inhibitors
- Gene Expression -- drug effects
- Iodide Peroxidase -- genetics
- Iodides -- pharmacokinetics
- Nitric Oxide -- metabolism
- Nitric Oxide Donors -- pharmacology
- Nitroprusside -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- RNA, Messenger -- metabolism
- Rats
- Signal Transduction -- drug effects
- Thyroglobulin -- genetics
- Thyroid Gland -- cytology
- Thyroid Hormones -- biosynthesis
- Thyrotropin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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