Silencing of STAT3 via Peptidomimetic LNP-Mediated Systemic Delivery of RNAi Downregulates PD-L1 and Inhibits Melanoma Growth. [electronic resource]
Producer: 20210329ISSN:- 2218-273X
- Animals
- B7-H1 Antigen -- antagonists & inhibitors
- Disease Models, Animal
- Down-Regulation
- Green Fluorescent Proteins -- metabolism
- HEK293 Cells
- HeLa Cells
- Humans
- Immune System
- Lipids -- chemistry
- Melanoma -- drug therapy
- Melanoma, Experimental -- drug therapy
- Mice
- Mice, Inbred C57BL
- Nanoparticles -- chemistry
- Neoplasm Transplantation
- Particle Size
- Peptidomimetics -- chemistry
- RNA Interference
- RNA, Small Interfering -- metabolism
- STAT3 Transcription Factor -- genetics
- Skin Neoplasms -- drug therapy
- Melanoma, Cutaneous Malignant
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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