Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo. [electronic resource]
Producer: 20170912Description: 629-644 p. digitalISSN:- 1432-0533
- Aniline Compounds -- chemistry
- Animals
- Antineoplastic Agents -- chemistry
- Astrocytoma -- drug therapy
- Benzimidazoles -- chemistry
- Brain Neoplasms -- drug therapy
- Cell Line, Tumor
- Cell Survival -- drug effects
- Colonic Neoplasms -- drug therapy
- Enzyme Inhibitors -- chemistry
- Escherichia coli
- Female
- Glutarates -- metabolism
- HEK293 Cells
- Humans
- Isocitrate Dehydrogenase -- antagonists & inhibitors
- Mice, Inbred BALB C
- Mice, Nude
- Mutation
- Recombinant Proteins -- genetics
- Sarcoma -- drug therapy
- Sf9 Cells
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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