Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6. [electronic resource]
Producer: 20050505Description: 2388-406 p. digitalISSN:- 0022-2623
- Animals
- Antineoplastic Agents -- chemical synthesis
- Biological Availability
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase 6
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- G1 Phase -- drug effects
- Humans
- Male
- Piperazines -- chemical synthesis
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Pyridines -- chemical synthesis
- Pyrimidines -- chemical synthesis
- Rats
- Rats, Sprague-Dawley
- Structure-Activity Relationship
- Thymidine -- metabolism
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Publication Type: Journal Article
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