Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2. [electronic resource]
Producer: 20150107Description: 1480-92 p. digitalISSN:- 1549-4918
- Adult
- Amino Acid Substitution
- Animals
- Body Patterning -- genetics
- Cell Differentiation
- Cell Line
- Cell Lineage
- HEK293 Cells
- Homeodomain Proteins -- genetics
- Humans
- Induced Pluripotent Stem Cells -- metabolism
- Male
- Mice
- Models, Biological
- Mutation -- genetics
- Phenotype
- Photoreceptor Cells -- metabolism
- Retina -- embryology
- Retinal Bipolar Cells -- metabolism
- Retinal Pigment Epithelium -- embryology
- Sequence Analysis, RNA
- Signal Transduction -- genetics
- Transcription Factors -- genetics
- Transcriptome -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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