Modifications to the tetracaine scaffold produce cyclic nucleotide-gated channel blockers with widely varying efficacies. [electronic resource]
Producer: 20051101Description: 5805-12 p. digitalISSN:- 0022-2623
- Animals
- Cattle
- Cyclic Nucleotide-Gated Cation Channels
- In Vitro Techniques
- Ion Channel Gating
- Ion Channels -- antagonists & inhibitors
- Membrane Potentials -- drug effects
- Oocytes -- drug effects
- Patch-Clamp Techniques
- Retinal Rod Photoreceptor Cells -- metabolism
- Structure-Activity Relationship
- Tetracaine -- analogs & derivatives
- Xenopus
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
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