An essential type I nitroreductase from Leishmania major can be used to activate leishmanicidal prodrugs. [electronic resource]
Producer: 20131203Description: 28466-76 p. digitalISSN:- 1083-351X
- Alleles
- Animals
- Cell Differentiation -- drug effects
- Cell Line
- Enzyme Inhibitors -- chemistry
- Female
- Flavin Mononucleotide -- metabolism
- Heterozygote
- Humans
- Kinetics
- Leishmania major -- drug effects
- Mice
- Mice, Inbred BALB C
- Mustard Compounds -- chemistry
- Nitroimidazoles -- chemistry
- Nitroreductases -- antagonists & inhibitors
- Prodrugs -- chemistry
- Substrate Specificity -- drug effects
- Trypanocidal Agents -- chemistry
No physical items for this record
Publication Type: Journal Article
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