Human schwannomas express activated platelet-derived growth factor receptors and c-kit and are growth inhibited by Gleevec (Imatinib Mesylate). [electronic resource]
Producer: 20090706Description: 5099-107 p. digitalISSN:- 1538-7445
- Antineoplastic Agents -- pharmacology
- Apoptosis
- Benzamides
- Blotting, Western
- Cell Cycle
- Cell Division -- drug effects
- Cell Line, Tumor
- Humans
- Imatinib Mesylate
- Magnetic Resonance Imaging
- Neurilemmoma -- metabolism
- Piperazines -- pharmacology
- Polymerase Chain Reaction
- Proto-Oncogene Proteins c-kit -- metabolism
- Pyrimidines -- pharmacology
- Receptors, Platelet-Derived Growth Factor -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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