Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents. [electronic resource]
Producer: 20140919Description: 447-55 p. digitalISSN:- 1768-3254
- Antineoplastic Agents -- chemical synthesis
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- HCT116 Cells
- Humans
- MCF-7 Cells
- Models, Molecular
- Molecular Structure
- Protein Kinase Inhibitors -- chemical synthesis
- Pyrimidines -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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