Effect of target dynamics on pharmacokinetics of a novel therapeutic antibody against the epidermal growth factor receptor: implications for the mechanisms of action. [electronic resource]
Producer: 20060928Description: 7630-8 p. digitalISSN:- 0008-5472
- Animals
- Antibodies, Monoclonal -- pharmacokinetics
- Carcinoma, Squamous Cell -- metabolism
- Colorectal Neoplasms -- metabolism
- Dose-Response Relationship, Immunologic
- ErbB Receptors -- biosynthesis
- Female
- Humans
- Immunoglobulin G -- metabolism
- Macaca fascicularis
- Male
- Mice
- Mice, Inbred BALB C
- Pancreatic Neoplasms -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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